Ma pupa, Henriette Le lettere di Eleonora Duse alla figlia

Le lettere di eleonora Duse alla figlia Enrichetta sono una fonte imprescindibile per la comprensione della figura artistica della grande attrice italiana. Questi documenti testimonino la ricchezza intellettuale e umana della donna e della madre

Pituitary gland abscess in a horse subsequent to head trauma

A 5‐year‐old Thoroughbred gelding with recent history of head trauma presented with multiple facial swellings, bilateral mucopurulent nasal discharge, neck pain, inappetence and depression. On computed tomographic examination, lesions within the pituitary fossa and structures adjacent to the right guttural pouch were identified. Soft tissue swelling was seen in the dorsal aspect of the right guttural pouch surrounding several cranial nerves, with fluid‐like material in the dependent portions of the right guttural pouch. A CSF sample revealed mild mixed pleocytosis and increased protein concentration. The horse had concurrent periapical disease of the 209‐cheek tooth and mild left sinusitis. The horse's demeanour deteriorated requiring euthanasia. Post‐mortem examination revealed a pituitary gland abscess

Semi High Speed Steels for Roughing Rolls with improved Thermal Fatigue Resistance

Thermal fatigue represents one of the most significant causes for roughing mill roll deterioration and possible failure. The materials ability to withstand thermal cycling is strictly correlated to its microstructural properties, which are the result of the solidification process and following heat treatment. Rolls for hot strip rolling mills are usually produced by centrifugal casting, without subsequent forging. A crucial role is played by the eutectic carbide network developing on solidification, which represents a preferential pattern for crack propagation. For this reason conventional highly alloyed HSS are not a popular substitute for traditional Chromium steel rolls in rougher stands. The so - called “semi-HSS”, containing less C (0.7-0.9 %C) and alloying elements are usually preferred by users requiring improved roll material. Specially developed “HSS for roughers” are being tested in various mills, but they are out of the scope of this paper. The present work is part of a continuing effort by INNSE Cilindri (RIVA Group) and Trento University to improve the “semi HSS” grades. In particular the thermal fatigue resistance of a new class of low-C semi HSS is evaluated. For purpose of comparison, both a conventional semi-HSS and a HSS grade were also considered. The test is based on induction heating (Tmax=670°C) and water cooling of cylindrical discs. Experimental results confirm the lower susceptibility towards heat checking of the new grades, containing reduced amount of eutectic carbides, the best behaviour being exhibited by a steel with a mixed martensite-bainite matrix microstructure

Simulated microgravity induces nuclear translocation of Bax and BCL-2 in glial cultured C6 cells

Alterations in the control of apoptotic processes were observed in cells during space flight or under simulated microgravity, the latter obtained with the 3D-Random Positioning Machine (3D-RPM). Usually the proteins Bax and Bcl-2, act as pro- or anti-apoptotic regulators. Here we investigated the effects of simulated microgravity obtained by the 3D-RPM on cell viability, localization and expression of Bax and Bcl-2 in cultures of glial cancerous cells. We observed for the first time a transient cytoplasmic/nuclear translocation of Bax and Bcl-2 triggered by changing gravity vector. Bax translocates into the nucleus after 1 h, is present simultaneously in the cytoplasm after 6 h and comes back to the cytoplasm after 24 h. Bcl-2 translocate into the nucleus only after 6 h and comes back to the cytoplasm after 24 h. Physiological meaning, on the regulation of apoptotic event and possible applicative outcomes of such finding are discussed

Utilizzo della risonanza magnetica nella diagnosi dell'edema contusivo intraosseo a livello di estremit\ue0 distale dell'equino : 6 casi

Bone Marrow Edema (BME) is a recently recognized entity. MRI has provided to be most powerful tool to asses BME, as the conventional imaging technique are unable to detect trabecular injuries. \u201cBone bruising\u201d describes the post-traumatic bone marrow changes demonstrated on MRI from a combination of haemorrhage, edema and microtrabecular fractures, described for the first time in the human knee in 1988. Bone bruise is a potentially important cause of orthopaedic pathology both in human and veterinary medicine, especially in sport horses. The term \u201cbruise\u201d indicates the traumatic origin of bone marrow changes. BME is defined as a region of hypointensity in T1 weighted sequences and hyperintensity in T2 and STIR sequences. Of 20 lame horses underwent MRI, six were included in the study, with pain localized at the fetlock region (5 cases) or hoof pain (1 case)

Planck-LFI: Design and Performance of the 4 Kelvin Reference Load Unit

The LFI radiometers use a pseudo-correlation design where the signal from the sky is continuously compared with a stable reference signal, provided by a cryogenic reference load system. The reference unit is composed by small pyramidal horns, one for each radiometer, 22 in total, facing small absorbing targets, made of a commercial resin ECCOSORB CR (TM), cooled to approximately 4.5 K. Horns and targets are separated by a small gap to allow thermal decoupling. Target and horn design is optimized for each of the LFI bands, centered at 70, 44 and 30 GHz. Pyramidal horns are either machined inside the radiometer 20K module or connected via external electro-formed bended waveguides. The requirement of high stability of the reference signal imposed a careful design for the radiometric and thermal properties of the loads. Materials used for the manufacturing have been characterized for thermal, RF and mechanical properties. We describe in this paper the design and the performance of the reference system.Comment: This is an author-created, un-copyedited version of an article accepted for publication in JINST. IOP Publishing Ltd is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. The definitive publisher authenticated version is available online at [10.1088/1748-0221/4/12/T12006]. 14 pages, 34 figure